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A case of aseptic meningitisaccompanied by myoclonus and peripheral eosinophiliahas been reported in a patient taking carbamazepine in combination with other medicationsThe patient was successfully dechallengedand the meningitis reappeared upon rechallenge with carbamazepine.
Because of the potential for serious adverse reactions in nursing infants from carbamazepinea decision should be made whether to discontinue nursing or to discontinue the drugtaking into account the importance of the drug to the mother.
Carbamazepine mustthereforebe considered to be carcinogenic in Sprague-Dawley ratsBacterial and mammalian mutagenicity studies using carbamazepine produced negative resultsThe significance of these findings relative to the use of carbamazepine in humans isat presentunknown.
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